Table 1.
Clinical and demographic characteristics of the study participants with depressive symptoms, compared to those without depressive symptoms and healthy controls.
| Total cohort (n = 198) |
Depression (n = 32) |
Depression controls (n = 166) |
Healthy controls (n = 106) |
Depression vs depression controls |
Depression vs healthy controls |
|||||||||
| mean ±SD |
mean ±SD |
mean ±SD |
mean ±SD |
|||||||||||
|
median |
(IQR) |
median |
(IQR) |
median |
(IQR) |
median |
(IQR) |
|||||||
| |
n (%) |
|
n (%) |
|
n (%) |
|
n (%) |
|
p-value |
p-value |
||||
| Age, years | 37 | (30– 43) | 36 | (32– 42) | 37.5 | (30– 43) | 38 | (30– 44) | NS | NS | ||||
| Female | 139 (70%) | 23 (72%) | 116 (70%) | 71 (67%) | NS | NS | ||||||||
| Weight, kg | 65 | (56– 73) | 66.03 ±13 | 65 | (57– 73) | 65 | (57– 73) | NS | NS | |||||
| BMI, kg/m2 | 22.88 | (21– 25) | 22.92 ±3 | 22.92 | (21– 25) | 23.02 | (21– 25) | NS | NS | |||||
| Autoimmune disease ever | 24 (12%) | 1 (3%) | 23 (14%) | 14 (13%) | NS | NS | ||||||||
| IBD IB celiacs ever | 33 (17%) | 3 (9%) | 30 (18%) | 21 (20%) | NS | NS | ||||||||
| Periodontitis ever | 44 (22%) | 7 (22%) | 37 (22%) | 22 (21%) | NS | NS | ||||||||
| Psych meds ever | 58 (29%) | 17 (53%) | 41 (25%) | 21 (20%) | < 0.005 | < 0.001 | ||||||||
| CTQ total | 31 | (27– 39) | 35 | (31– 56) | 30 | (27– 39) | 29 | (27– 34) | < 0.005 | < 0.001 | ||||
| WHOQOL | ||||||||||||||
| DOM1 | 15.43 | (14– 17) | 12.8 ±3 | 16 | (14– 17) | 16.57 | (15– 18) | < 0.001 | < 0.001 | |||||
| DOM2 | 14.00 | (12– 16) | 11.04 ±2 | 14.67 | (13– 16) | 15.55 ±2 | < 0.001 | < 0.001 | ||||||
| DOM3 | 13.33 | (11– 16) | 11.21 ±4 | 13.33 | (12– 16) | 14.67 | (12– 17) | < 0.001 | < 0.001 | |||||
| DOM4 | 15.50 | (14– 17) | 13.5 ±3 | 15.5 | (15– 17) | 16.3 ±2 | < 0.001 | < 0.001 | ||||||
| OV QOL GH | 7.00 | (6– 8) | 6 | (4– 7) | 8 | (6– 8) | 8 | (7– 9) | < 0.001 | < 0.001 | ||||
| PCL Total | 10.00 | (9– 12) | 26.42 ±20 | 9 | (3– 19) | 5 | (2– 14) | < 0.005 | < 0.001 | |||||
| PTSD symptoms | 16 (81%) | 9(28%) | 7 (4%) | 0 | < 0.001 | < 0.001 | ||||||||
| CESD Total | 10 | (5– 19) | 33.53 ±5 | 9 | (4– 13) | 6 | (3– 10) | < 0.001 | < 0.001 | |||||
| STAI | ||||||||||||||
| State Total | 38 | (31– 47) | 53.16 ±10 | 36 | (30– 43) | 32 | (27– 36) | < 0.001 | < 0.001 | |||||
| Trait Total | 42 | (35– 51) | 57.06 ±7 | 40.5 | (34– 47) | 36 | (33– 41) | < 0.001 | < 0.001 | |||||
| State anxiety symptoms | 74 (37%) | 28 (88%) | 46 (28%) | 0 | < 0.001 | < 0.001 | ||||||||
| Trait anxiety symptoms | 81 (41%) | 32 (100%) | 49 (30%) | 0 | < 0.001 | < 0.001 | ||||||||