Table 3.

Radical SAM enzyme families were included in this study.

Name	Description
LipA	Lipoyl synthases
MTTase	Methylthiotransferases
MTaseA	Class A Methyltransferase
B12-binding	B12-binding domain containing
HemN	HemN (Coproporphyrinogen III oxidase) homologs
Elp3	Elp3 (Elongator complex subunit) homologs
BATS	BATS domain containing
Viperin	Antiviral proteins
SPASM	SPASM or twitch auxiliary domain containing
Activating Enzyme	Activating enzymes
QueE	QueE (7-carboxy-7-deazaguanine synthase) homologs
TYW1	TYW1 homologs
PLP-dependent	Pyridoxal 5’-phosphate dependent