Figure 3.

Comparisons of csDEG detection accuracy. (A) True discovery rate (TDR) is shown along the identified top-ranking genes in cell type six (left). The average TDR (right) is the aggregated results across six cell types. TDR is defined as the proportion of true csDEG, among all top-ranking genes, at a given cutoff. (B): Model-specific sensitivity and type I error rates averaged across six cell types. (C): Averaged type I error versus sensitivity for all eight models. N=20 simulations are conducted in each setting.