Skip to main content
. 2022 Dec 6;24(1):bbac516. doi: 10.1093/bib/bbac516

Figure 8.

Figure 8

Real data analysis for a set of IBD RNA-seq dataset (GEO: GSE57945). (A) Venn diagram showing the overlapped csDEG from CARseq, DESeq2, TOAST, TCA and LRCDE. (B) and (C) illustrate the maximal and minimal pairwise overlapping csDEG among all the methods. (D) Relevant pathways identified by the significant and overlapped csDEG in (B) and (C). (E) Scatterplots of computed FDR values across two pairwise comparisons. Correlation coefficients are shown in red color. (F) For each method, the model-specific csDEG level is shown. The higher value indicates a more liberal model. The model-specific csDEG level is defined as the ratio between model-specific csDE genes number and consensus-called genes number. (G) shows model accuracies based on pseudo-bulk RNA-seq data derived from a real single-cell dataset. The left panel shows the TDR of the top-ranking genes and the right panel shows sensitivities across strata.