Table 3.

ROC Curves for Different Outcomes in Patients With AF and Cancer

Area under the curve (95% CI)
Variable	Any bleeding	Major bleeding	ICH	GB
HAS‐BLED score (continuous)	0.809 (0.808–0.810)	0.774 (0.772–0.776)	0.744 (0.740–0.748)	0.752 (0.749–0.755)
HAS‐BLED score ≥3	0.753 (0.751–0.754)	0.716 (0.714–0.718)	0.698 (0.694–0.702)	0.702 (0.699–0.704)
ATRIA score (continuous)	0.768 (0.766–0.769)	0.777 (0.774–0.779)	0.635 (0.629–0.641)	0.728 (0.725–0.731)
ATRIA score ≥5	0.678 (0.676–0.680)	0.700 (0.698–0.702)	0.563 (0.557–0.568)	0.662 (0.659–0.665)
ORBIT score (continuous)	0.918 (0.917–0.918)	0.870 (0.869–0.871)	0.742 (0.738–0.745)	0.825 (0.822–0.827)
ORBIT score ≥4	0.813 (0.811–0.814)	0.805 (0.804–0.807)	0.641 (0.635–0.646)	0.756 (0.753–0.758)

AF indicates atrial fibrillation; ATRIA, anemia, severe renal disease (eg, dialysis), age ≥75 years, prior bleeding, and hypertension; GB, gastrointestinal bleeding; HAS‐BLED, uncontrolled hypertension (systolic blood pressure >160 mm Hg), abnormal kidney (dialysis or transplant)/liver function (ie, cirrhosis), previous stroke, bleeding history or predisposition, elderly age (≥65 years), and drug (antiplatelet, nonsteroidal anti‐inflammatory drugs)/alcohol abuse; ICH, intracranial hemorrhage; ORBIT, older age ≥75 years, anemia, bleeding history, chronic kidney disease, and treatment with antiplatelet drugs; and ROC, receiver operating characteristic.