Table 5.
C‐Statistics for HAS‐BLED Score Against ICH, According to Each Cancer Type
| Type of cancer | No. of patients (descending order) | C‐statistic (95% CI) for ICH | |
|---|---|---|---|
| HAS‐BLED score continuous | HAS‐BLED score ≥3 | ||
| All cancers | 399 344 | 0.74 (0.74–0.75) | 0.70 (0.69–0.70) |
| Metastatic cancer | 97 606 | 0.75 (0.73–0.76) | 0.71 (0.69–0.72) |
| Prostatic cancer | 62 710 | 0.72 (0.71–0.73) | 0.67 (0.67–0.68) |
| Colorectal cancer | 54 755 | 0.74 (0.73–0.75) | 0.69 (0.68–0.70) |
| Lung cancer | 49 737 | 0.75 (0.73–0.76) | 0.70 (0.68–0.72) |
| Breast cancer | 38 699 | 0.80 (0.79–0.81) | 0.75 (0.74–0.76) |
| Bladder cancer | 32 342 | 0.69 (0.67–0.71) | 0.64 (0.63–0.65) |
| Leukemia | 19 148 | 0.70 (0.68–0.72) | 0.66 (0.65–0.68) |
| Lymphoma | 17 986 | 0.74 (0.72–0.76) | 0.71 (0.69–0.72) |
| Renal cancer | 13 294 | 0.71 (0.68–0.74) | 0.64 (0.63–0.66) |
| Myeloma | 13 081 | 0.71 (0.69–0.74) | 0.67 (0.64–0.69) |
| Liver cancer | 9261 | 0.69 (0.65–0.73) | 0.61 (0.59–0.63) |
| Gastric cancer | 8470 | 0.75 (0.71–0.79) | 0.70 (0.67–0.74) |
| Pancreas cancer | 8409 | 0.78 (0.75–0.82) | 0.74 (0.71–0.77) |
| Uterine cancer | 7670 | 0.74 (0.70–0.78) | 0.69 (0.66–0.72) |
| Ovarian cancer | 4494 | 0.79 (0.73–0.84) | 0.73 (0.68–0.78) |
HAS‐BLED indicates uncontrolled hypertension (systolic blood pressure >160 mm Hg), abnormal kidney (dialysis or transplant)/liver function (ie, cirrhosis), previous stroke, bleeding history or predisposition, elderly age (≥65 years), and drug (antiplatelet, nonsteroidal anti‐inflammatory drugs)/alcohol abuse; and ICH, intracranial hemorrhage.