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. 2022 Dec 6;11(23):e027295. doi: 10.1161/JAHA.122.027295

Table 1.

Characteristics of Study Population

Characteristics All (N=272) NCI (n=74) CIND (n=99) AD (n=78) VaD (n=21)
Age, mean (SD), y 75.42 (6.77) 72.93 (7.52) 77.01 (5.87) 75.9 (6.45) 74.67 (7.07)
Sex, n (%)
Female 157 (57.72) 44 (59) 51 (52) 55 (71) 7 (33)
Education, mean (SD), y 7.32 (5.04) 9.64 (4.82) 8.1 (5.03) 4.63 (4.43) 5.48 (2.52)
Ethnicity, n (%)
Chinese 237 (87.13) 68 (92) 86 (87) 67 (86) 16 (76)
Malay 18 (6.62) 3 (4) 4 (4) 7 (9) 4 (19)
Indian 14 (5.15) 2 (3) 8 (8) 3 (4) 1 (5)
Others * 3 (1.10) 1 (1) 1 (1) 1 (1) 0 (0)
Vascular risk factors, n (%)
Hypertension 179 (65.80) 40 (54) 63 (64) 55 (71) 21 (100)
Diabetes 83 (30.51) 12 (16) 28 (28) 32 (41) 11 (52)
Hyperlipidemia 191 (70.22) 53 (72) 67 (68) 53 (68) 18 (86)
Current smoking 12 (4.41) 4 (5) 5 (5) 1 (1) 2 (10)
History of CVD, n (%)
Myocardial infarction 11 (4.04) 2 (3) 5 (5) 2 (3) 2 (10)
Atrial fibrillation 13 (4.78) 1 (1) 9 (9) 1 (1) 2 (10)
Coronary angioplasty 9 (3.31) 2 (3) 3 (3) 2 (3) 2 (10)
Coronary bypass procedure 7 (2.57) 1 (1) 4 (4) 2 (3) 0 (0)
Heart failure 3 (1.10) 1 (1) 2 (2) 0 (0) 0 (0)
Stroke 49 (18.01) 5 (7) 17 (17) 10 (13) 17 (81)
Blood pressure, mm Hg
Systolic 142 (19) 139 (19) 140 (18) 147 (21) 147 (18)
Diastolic 73 (11) 73 (10) 71 (10) 74 (11) 78 (14)
Mean arterial pressure, mm Hg 96 (12) 95 (11) 94 (11) 98 (12) 101 (14)
Heart rate, bpm 61 (10) 59 (8) 61 (10) 61 (10) 69 (14)
Pulse pressure, mm Hg 70 (17) 66 (17) 69 (16) 73 (17) 69 (16)

AD indicates Alzheimer disease; bpm, beats per minute; CIND, cognitive impairment no dementia; CVD, cardiovascular disease; NCI, no cognitive impairment; and VaD, vascular dementia.

*

Other ethnicities include those who are Eurasians, or have mixed‐ethnicities (e.g., Chinese‐Malay, Chinese‐Indian, Malay‐Indian).