Table 2.
The eQTLs of BAG3 and Their Associations With Cardiomyopathies
| SNP | Expression of BAG3 | pval.eQTL | pval.cardiomyopathy | effect_allele.eQTL | beta.eQTL | beta.cardiomyopathy | EAF | r2 with p.Cys151Arg |
|---|---|---|---|---|---|---|---|---|
| rs196334 | Artery tibial | 7.29E‐06 | 2.85E‐08 | T | −0.176 | −0.177 | 0.546 | 0.139 |
| rs196336 | Skin sun‐exposed lower leg | 3.93E‐19 | 2.93E‐08 | C | −0.346 | −0.178 | 0.546 | 0.139 |
| rs196298 | Colon sigmoid | 2.74E‐06 | 8.62E‐07 | A | −0.316 | −0.178 | 0.264 | 0.063 |
| rs171910 | Muscle skeletal | 2.00E‐06 | 5.01E‐03 | G | −0.224 | −0.101 | 0.738 | 0.076 |
| rs17099080 | Adipose subcutaneous | 1.06E‐05 | 7.24E‐03 | C | 0.224 | 0.098 | 0.253 | 0.034 |
| rs111384142 | Heart atrial appendage | 1.25E‐06 | 0.103 | T | −1.084 | −0.266 | 0.010 | 0.016 |
| rs11598594 | Skin not sun exposed suprapubic | 1.01E‐05 | 0.851 | C | −0.799 | −0.038 | 0.006 | 0.005 |
| rs3887073 | Brain anterior cingulate cortex BA24 | 4.32E‐07 | 0.938 | T | 0.398 | −0.004 | 0.103 | 0.005 |
BAG3 indicates Bcl‐2–associated athanogene 3; EAF, effect allele frequency; eQTL, expression quantitative trait locus; and SNP, single nucleotide polymorphism.