Table 3. Antigens and epitopes preferentially recognized by patients’ IgG at the end of treatment (T3).
| Patient | Antigen | Accession | Frequency (%) | Consensus sequence |
|---|---|---|---|---|
| 1 | <17.2% in-frame inserts | |||
| 2 | Putative surface antigen 2 (CA-2) | PWU84979.1 | 100.00 | FGQAAAGDKPPPFGQAAAGDKPSPFGQ |
| 3 | Putative surface antigen 2 (CA-2) Putative microtubule-associated protein Putative surface antigen 2 (CA-2) Putative trans-sialidase |
PWU84979.1 PWU97874.1 PWU84979.1 PWU87189.1 |
60.12 27.98 11.31 0.60 |
AAGDKPPPFGQAAAGEKPSP VDPDHFRSTTQDAYRPVDPSAYK FGQAAAGDKPPPFGQA MPAGTSEEGSRDDSSMPAGT |
| 4 | <17.2% in-frame inserts | |||
| 5 | <17.2% in-frame inserts | |||
| 6 | <17.2% in-frame inserts | |||
| 7 | <17.2% in-frame inserts | |||
| 8 | <17.2% in-frame inserts | |||
| 9 | <17.2% in-frame inserts | |||
| 10 | <17.2% in-frame inserts | |||
| 11 | Putative surface antigen 2 (CA-2) Putative microtubule-associated protein Putative surface antigen 2 (CA-2) Putative surface antigen 2 (CA-2) |
PWU84979.1 PWU97874.1 PWU84979.1 PWU84979.1 |
94.25 4.60 0.57 0.57 |
SPFGQAAAGDKPPPFGQAAAGDKPSPFG ALPQEEEEDVGPRHVDPDHFRSTTQDA DKPSLFGQAAAGDNPSPFGQAAAGDK DKPSPFGQAAGGEKPPPFGPAAAGDK |
| 12 | Putative trans-sialidase Putative surface antigen 2 (CA-2) R27-2 protein Putative trans-sialidase |
PWU87189.1 PWU84979.1 XP_818212.1 PWU87189.1 |
89.89 6.84 3.16 0.11 |
MPAGTSEEGSRGDNSMPAGASEEGSRG DKPPPFGQAAAGDKPSLFGQAAAGDKP KVAEAEKQRAAEATKVAEAEKQR SSMPAGTSQEGIRDDRSMRGGASEEGSRDD |
| 13 | Putative surface antigen 2 (CA-2) Hypothetical protein C4B63_22g72 Putative surface antigen 2 (CA-2) |
PWU84979.1 PWU95420.1 PWU84979.1 |
99.97 0.02 0.01 |
SPFGQAAAGDKPPPFGQAAAGDKPSPFGQAAAG QEGQAETKRNSVRRGDDPPSAAATPAGTT DKPPPFGQAASGEKPSPFGKAAAGEKPSPF |
| 14 | <17.2% in-frame inserts | |||
| 15 | <17.2% in-frame inserts | |||
| 16 | <17.2% in-frame inserts | |||
| 17 | Putative surface antigen 2 (CA-2) Putative microtubule-associated protein Hypothetical protein |
PWU84979.1 PWU97874.1 XP_803285.1 |
97.78 1.14 1.09 |
AAGDKPSPFGQAAAGDKPPPFGQAAAGDKP QEDVGPRHVDPDHFRSTTQD SRHWWQCHEWRGTGRAQGLGVEMLVKAKDGGSEPLT |
| 18 | <17.2% in-frame inserts | |||
| 19 | Putative surface antigen 2 (CA-2) Putative surface antigen 2 (CA-2) |
PWU84979.1 PWU84979.1 |
93.81 6.19 |
AAAGDKPSPFGQAAAGDKPSPFG PPFGQAAADDKPPPFGQAAAGEK |
| 20 | <17.2% in-frame inserts | |||