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. Author manuscript; available in PMC: 2023 Jan 19.
Published in final edited form as: Front Nanotechnol. 2022 Aug 15;4:955022. doi: 10.3389/fnano.2022.955022

FIGURE 6.

FIGURE 6

Effect of lutein ND on UV irradiation-induced ROS generation in cultured ARPE-19 cells. Cells were incubated for 72 h in media only, media plus 0.4% DMSO, EYPC rHDL, lutein (8.8 μM in DMSO), and lutein ND (8.8 μM as lutein). Following incubation, cells in indicated treatment groups were exposed to UV irradiation for 2 h. Following irradiation, cellular ROS levels were determined. For assay readout, sample fluorescence emission was measured at 535 nm (excitation 485 nm). Statistical values reported are the mean ± standard error (n = 10); ** = p < 0.01 vs. control, *** = p < 0.001 vs. control, **** = p < 0.0001 vs. control. Ns = not significant.