TABLE 3.
Associations Between Daily Biomarker Quartiles and Delirium Versus Normal and Coma Versus Normal Observed the Following Day (n = 197)a
| Variable | Delirium vs Normal | Coma vs Normal | ||
|---|---|---|---|---|
| OR (95% CI) | p | OR (95% CI) | p | |
| Model 1: C-reactive protein quartile | 1.05 (0.85–1.30) | 0.655 | 1.36 (1.03–1.79) | 0.030 |
| Model 2: d-dimer quartile | 1.49 (1.14–1.94) | 0.003 | 1.52 (1.08–2.14) | 0.017 |
| Model 3: Ferritin quartile | 1.33 (1.04–1.70) | 0.026 | 1.59 (1.14–2.23) | 0.007 |
OR = odds ratio.
a
Results were obtained from generalized mixed-effects multinomial models with daily outcomes with three levels (delirium, coma, or cognitively normal) adjusting for age, race, sex, daily Acute Physiology and Chronic Health Evaluation-II calculated on day of delirium or coma assessment, Charlson Comorbidity Index, hypertension, daily mechanical ventilation status, and time (d).