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. Author manuscript; available in PMC: 2024 Jan 5.

Published in final edited form as: Int J Pharm. 2022 Nov 24;630:122423. doi: 10.1016/j.ijpharm.2022.122423

Table 5.

Fit summary for both responses.

Model	Response
	Release at 0.5 h		Release at 6 h
	Adjusted R²	Predicted R²	Adjusted R²	Predicted R²
Linear	0.8080	0.7389	0.4096	0.1613
Quadratic	0.9889	0.8925	0.9354	0.8017
Special cubic	0.9713		0.9975
Cubic	1.0000		1.0000