Table 9.

Weight, thickness, surface pH, and drug content of hot-melt extruded ciprofloxacin hydrochloride ocular inserts (mean ± SD, n = 3).

Formulation	Weight (mg)	Thickness (mm)	Surface pH	Drug content (%)
F1	5.1 ± 0.02	0.9 ± 0.03	7.3 ± 0.00	91.2 ± 1.0
F2	5.2 ± 0.10	0.8 ± 0.03	7.4 ± 0.02	94.0 ± 1.1
F3	5.1 ± 0.05	1.0 ± 0.01	7.4 ± 0.01	100.7 ± 4.9
F4	5.1 ± 0.04	1.0 ± 0.02	7.0 ± 0.04	90.8 ± 1.3
F5	5.2 ± 0.03	0.9 ± 0.02	7.4 ± 0.01	96.3 ± 2.4
F6	5.1 ± 0.02	0.9 ± 0.02	7.3 ± 0.00	90.1 ± 1.4
F7	5.1 ± 0.02	1.1 ± 0.01	7.1 ± 0.01	101.4 ± 1.2
F8	5.1 ± 0.04	0.9 ± 0.02	7.3 ± 0.01	91.7 ± 0.5
F9	5.2 ± 0.10	1.0 ± 0.01	7.3 ± 0.01	90.9 ± 2.1
F10	5.1 ± 0.04	1.0 ± 0.02	7.4 ± 0.01	91.3 ± 1.5
F11	5.1 ± 0.03	1.0 ± 0.01	7.4 ± 0.00	92.4 ± 1.7
F12	5.3 ± 0.06	1.1 ± 0.01	7.4 ± 0.00	92.5 ± 2.3
F13	5.3 ± 0.15	1.1 ± 0.02	7.2 ± 0.00	92.1 ± 2.4
F14	5.0 ± 0.01	0.9 ± 0.03	7.4 ± 0.01	90.3 ± 1.5
F15	5.3 ± 0.09	0.9 ± 0.04	7.4 ± 0.01	93.4 ± 1.4
F16	5.2 ± 0.10	1.0 ± 0.02	7.4 ± 0.00	91.0 ± 1.8
F17	5.2 ± 0.04	1.0 ± 0.01	7.2 ± 0.06	96.4 ± 2.0
F18	5.1 ± 0.11	1.1 ± 0.02	7.4 ± 0.00	91.9 ± 1.9
F19	5.2 ± 0.14	1.0 ± 0.01	7.3 ± 0.01	98.6 ± 3.3
F20	5.1 ± 0.06	1.0 ± 0.02	7.4 ± 0.01	96.8 ± 1.3