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. 2022 Dec 22;30(1):38–51. doi: 10.1038/s41594-022-00892-7

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 6 — Comparative analysis of genome organization and heterochromatic marks across HCT116, HFFc6, IMR90, K562, GM12878 and H1-hESC. (a) Expanded example domain across cell types as in Fig. 3e including data for IMR-90 and HFFc6. (b) Stacked signal heatmaps of H3K9me3 signal centered at the top 200 largest H3K9me3 domains detected in six cell types. (c) Example of homotypic interactions at H3K9me3-HP1α domains on chr19 in H1-hESC.