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Properties of inactive IPGs in HCT116
| B0 | B1 (facultative) | B4 (constitutive) | |
|---|---|---|---|
| Histone modifications | H3K9me2 | H3K27me3 | H3K9me3 |
| Factors/histone variants | H2A.Z | PRC2, EZH2 | HP1α, HP1β |
| Replication timing (RT) | late | late | very late |
| RIF1-sensitive RT | + | − | − |
| CpG methylation | + | − | −− |
| 3D self-affinity | − | + | ++ |
| Protect-seq | − | + | ++ |
| Cohesin permissive | + | + | + |
| CTCF permissive | + | + | − |
| LaminB1/B2 | + | + | + |
Symbol legend: −−, very low; −, low; +, high; ++, very high.
