Table 1:
Genotype | Induction | Abbreviation |
---|---|---|
C57Bl/6 | none | C57Bl/6 |
Panx1 fl/fl | tamoxifen | Panx1fl/fl |
Panx1fl/fl / Myh11-CreERT2+ | tamoxifen | iSMC Panx1 KO |
Panx1fl/fl / Cdh5-CreERT2+ | tamoxifen | iEC Panx1 KO |
ROSA26-Panx1TG / Myh11-CreERT2+ | tamoxifen | iSMC Panx1 OE |
ROSA26-Panx1TG / Myh11-CreERT2− | tamoxifen | TG Tamox Control |
ROSA26-Panx1TG / Myh11-CreERT2+ | peanut oil | TG Geno Control |
Panx1 −/− | tamoxifen | Panx1KO |
Panx1−/− / ROSA26-Panx1TG / Myh11-CreERT2+ | tamoxifen | Panx1KO-iSMC OE |
Panx1−/− / ROSA26-Panx1TG / Myh11-CreERT2− | tamoxifen | Panx1KO-TG Tamox Control |
Panx1−/− / ROSA26-Panx1TG / Myh11-CreERT2+ | peanut oil | Panx1KO-TG Geno Control |