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. Author manuscript; available in PMC: 2023 Jan 20.
Published in final edited form as: Nat Biotechnol. 2022 Oct 10;41(1):128–139. doi: 10.1038/s41587-022-01474-0

Extended Data Fig. 3 |. Comparison of the drug screening results using different interactomes and their combinations.

Extended Data Fig. 3 |

(a) 16 drugs identified by our interactome cannot be identified by any of the other three interactomes (and the interactome combined from them for 13 drugs) compared in this study. 6 of the top 23 drugs with desired anti-SARS-CoV-2 profiles are among these drugs. (b) Drugs identified by combining all four interactomes that could not be identified by any interactome individually. Three drugs (highlighted with a star) were found to have desired anti-SARS-CoV-2 profiles.