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. 2023 Jan 20;26(2):105981. doi: 10.1016/j.isci.2023.105981

Figure 5.

Figure 5

Changes in the exposure of RBD residues induced by the Omicron variant

(A) Per-residue changes in solvent-accessible surface area (SASA) between the Omicron and WT spikes’ RBD (see STAR Methods for details). SASA for each residue is divided by the number of atoms in that residue.

(B) Relative SASA changes offset by the mean in the closed state mapped on the RBD structure.

(C) SASA changes offset by the values in the closed state, i.e., the mean value between PC1 = 0 and PC1 = 12. The mean value from PC1 = −30 to PC1 = −16 is color-coded on the structure in panel B.