Table 2.

Arterial Hemodynamics of Participants with T1D

	Placebo	Bromocriptine	P-value
Pressure Hemodynamics
Systolic blood pressure (mm Hg)	118 ± 9	113 ± 11	<0.001
Diastolic blood pressure (mm Hg)	69 ± 6	66 ± 7	0.039
Pulse pressure (mm Hg)	49 ± 7	46 ± 8	0.015
Mean arterial pressure (mm Hg)	88 ± 7	85 ± 8	0.002
Ascending Aorta
Pulse Wave Velocity (m/s)	4.0 ± 0.8	3.7 ± 0.6	0.018
Relative Area Change (%)	28.1 ± 6.8	30.7 ± 5.7	0.083
Distensibility (%/mm Hg)	0.59 ± 0.17	0.68 ± 0.17	0.017
Descending Aorta
Pulse Wave Velocity (m/s)	4.2 ± 0.6	4.1 ± 0.8	0.278
Relative Area Change (%)	25.9 ± 4.5	26.2 ± 5.7	0.779
Distensibility (%/mm Hg)	0.55 ± 0.12	0.59 ± 0.16	0.079
Abdominal Aorta
Pulse Wave Velocity (m/s)	4.2 ± 0.6	3.9 ± 0.4	0.007
Relative Area Change (%)	26.1 ± 3.8	27.3 ± 3.4	0.158
Distensibility (%/mm Hg)	0.56 ± 0.15	0.61 ± 0.11	0.013
Endothelial Function
Reactive Hyperemia Index	2.30 ± 0.56	1.99 ± 0.57	0.006
LN reactive hyperemia index	0.81 ± 0.23	0.65 ± 0.28	0.003
Framingham RHI Risk Score	0.87 (0.55 – 1.04)	0.75 (0.25 – 0.99)	0.010
Peripheral Vascular Stiffness
Brachial compliance (mL/mmHg)	0.059 ± 0.012	0.061 ± 0.013	0.156
Brachial distensibility (%/mmHg)	6.06 ± 1.16	6.25 ± 1.15	0.303

Data reported as mean ± SD or as median with corresponding IQR. LN = natural logarithm.