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. Author manuscript; available in PMC: 2024 Feb 1.
Published in final edited form as: Br J Haematol. 2022 Oct 20;200(3):358–366. doi: 10.1111/bjh.18507

Table 5.

Multiple linear regression among preschool patients diagnosed with sickle cell disease

BRIEF-P Working Memory a BRIEF-P Global Executive a BBCS-3:R School Readiness b SB-5 Working Memory b
Estimate SE p Estimate SE p Estimate SE p Estimate SE p
Intercept 87.81 23.76 <0.001 88.45 25.11 <0.001 72.22 29.89 0.018 48.76 25.89 0.064

Sex 2.40 2.90 0.411 3.54 3.06 0.251 1.13 3.64 0.757 −2.14 3.17 0.503

Genotype 2.89 2.90 0.323 1.91 3.07 0.535 −5.35 3.71 0.154 −0.17 3.18 0.956

Parent Education −3.34 3.73 0.374 −1.27 3.94 0.749 17.37 4.74 <0.001 7.48 4.02 0.067

Age at assessment −3.10 3.97 0.437 −3.83 4.19 0.364 0.69 4.99 0.890 5.99 4.36 0.174

Early Development Index −0.18 0.09 0.044 −0.20 0.09 0.036 0.11 0.11 0.330 0.14 0.10 0.142

BRIEF-P, Behavior Rating Inventory of Executive Function - Preschool; SB-5, Stanford-Binet Intelligence Scales – Fifth Edition; BBCS-3:R, Bracken Basic Concept Scale – 3rd Edition: Receptive.

Performance measures included the Stanford-Binet Intelligence Scales – Fifth Edition and the Bracken Basic Concepts Scale – Third Edition: Receptive. Parent ratings of executive functioning collected using the Behavior Rating Inventory of Executive Function – Preschool Version.

a

Higher scores indicative of greater symptoms (i.e., more problems)

b

Higher scores indicative of better performance