Table 2.

Convertase directed regulators of complement activation (reproduced from reference 23)

Regulator	regulatory activity decay / cofactor		regulated pathway	main regulatory compartment
CR1	DAA	CA	CP/LP & AP	surface
DAF	DAA	-	CP/LP & AP	surface
MCP	-	CA	CP/LP & AP	surface
C4BP	DAA	CA	CP/LP	fluid/surface
Factor H	DAA	CA	AP	fluid/surface
FHL-1	DAA	CA	AP	fluid/surface
Factor I	Protease for degradation of C3b or C4b in presence of a cofactor		CP/LP & AP	fluid (on surface only in conjunction with cofactor)