Skip to main content
. Author manuscript; available in PMC: 2024 Feb 15.
Published in final edited form as: Biol Psychiatry. 2022 Sep 16;93(4):370–381. doi: 10.1016/j.biopsych.2022.09.010

Figure 5: Molecular comparison of the left and right CeA in pain and non-pain mice.

Figure 5:

A, B) Representative immunohistochemistry for CGRP in the left (A) and right (B) CeA of saline treated mice. C, D) Representative immunohistochemistry for CGRP in the left (C) and right (D) CeA of CYP-treated mice. E) Quantified fluorescence intensity of CGRP in the left and right CeA of saline and CYP mice. F, G, H, J, K, L) Representative RNAscope for Calcrl (F, J), Sst (G, K), and Prkcd (H, L) in the CeA. I, M) Representative merge to show co-localization (fuchsia arrowhead: Calcrl only, yellow arrowhead: Sst only, white arrowhead: Prkcd only, filled yellow arrowhead: Calcrl and Sst, filled white arrowhead: Calcrl and Prkcd). N) Percent of Calcrl-positive cells in the left and right CeC of saline and CYP mice. O) Percent of Sst-positive cells in the left and right CeC of saline and CYP mice. P) Percent of Prkcd-positive cells in the left and right CeC of saline and CYP mice. Q) Percent of Sst and Prkcd-positive cells in the left and right CeC of saline and CYP mice. R) Percent of Calcrl-positive cells that also express Sst in the left and right CeC of saline and CYP mice. S) Percent of Calcrl-positive cells that also express Prkcd in the left and right CeC of saline and CYP mice. All data are presented as mean +/− SEM and error bars represent SEM. *P<0.05 **P<0.01. See supplementary table 1 for further statistical information.