Table 3.
Survival of recurrent glioma patient groups according to tracer uptake
All recurrent glioma cases | PRS (median; months) | p-value | TTF (median; months) | p-value |
---|---|---|---|---|
All diagnoses (n = 88) SUVmax ≤ 1.68 (n = 44) SUVmax > 1.68 (n = 44) |
27.9 41.6 12.6 |
< 0.001 |
8.7 14.9 6.2 |
< 0.001 |
All IDH-wildtype (n = 42) SUVmax ≤ 1.89 (n = 21) SUVmax > 1.89 (n = 21) |
10.6 Not reached 8.2 |
0.002 |
6.1 5.4 6.8 |
0.142 |
All IDH-mutant (46) SUVmax ≤ 1.60 (n = 23) SUVmax > 1.60 (n = 23) |
36.9 41.6 25.3 |
0.031 |
18.4 32.2 8.7 |
0.001 |
All astrocytoma, IDH-mutant (28) SUVmax ≤ 1.72 (14) SUVmax > 1.72 (14) |
27.9 36.9 13.5 |
0. 009 |
11.7 22.6 6.2 |
0.007 |
Astrocytoma WHO 2021 grade 3, IDH mutant (17) SUVmax ≤ 1.55 (9) SUVmax > 1.55 (8) |
36.9 36.9 13.1 |
0.015 |
11.7 32.2 2.7 |
0.025 |
All low-grade (2 or 3) astrocytoma, IDH-mutant (18) SUVmax ≤ 1.33 (9) SUVmax > 1.33 (9) |
36.9 36.9 13.1 |
0.003 |
14.5 32.2 6.2 |
0.063 |
All oligodendroglioma, IDH-mutant and 1p/19q codeleted (18) SUVmax ≤ 1.28 (9) SUVmax > 1.28 (9) |
Not reached Not reached Not reached |
0.464 |
Not reached Not reached 18.4 |
0.147 |
SUVmax maximum standardized uptake value, IDH isocitrate dehydrogenase, PRS post recurrence survival, TTF time to treatment failure