Table 3.

ORs with 95% CIs for the associations between month-specific 25(OH)D z-score (as summary variable) and T2DM in women and men. The Tromsø Study 1986–2016

	T1–T3				T3–T5
	Δ25(OH)Da		AUC 25(OH)Db		Δ25(OH)Dc
	Crude OR (95% CI)	Adjustedd OR (95% CI)	Crude OR (95% CI)	Adjustedd OR (95% CI)	Crude OR (95% CI)	Adjustede OR (95% CI)
Women	0.45* (0.29, 0.70)	0.51* (0.32, 0.80)	0.80 (0.63, 1.02)	0.85 (0.64, 1.12)	2.21* (1.37, 3.56)	2.48* (1.39, 4.43)
Men	0.48* (0.31, 0.74)	0.52* (0.33, 0.84)	1.07 (0.85, 1.34)	1.23 (0.88, 1.57)	2.09* (1.05, 4.18)	1.93 (0.90, 4.12)

25(OH)D 25-hydroxyvitamin D, CI confidence interval, OR odds-ratio, T time-point

*p value < 0.05

^aChange in month-specific 25(OH)D z-score from T1 to T3

^bAUC for month-specific 25(OH)D z-scores for pre-diagnostic samples

^cChange in month-specific 25(OH)D z-score from T3 to T5

^dAdjusted for age, body mass index, weight change, and physical activity at T1

^eAdjusted for age, body mass index, weight change, and physical activity at T3