Fig. 4. Delayed inhibition of BLA neuronal nerve terminals in the NAc core after the time window of memory reconsolidation fails to affect the consolidated MeAM-associated memory.
A Diagram of the virus infusion and cannulas implantation sites and the experimental procedure. CNO (2 µg/side) or vehicle was infused into the NAc core 18 h after the CPP test. B Delayed CNO infusion failed to affect MeAM-associated memory in hM4Di-expressing mice. Mixed two-way ANOVA, the drug × test interaction, F[2,18] = 0.05, p = 0.95; n = 5 and 6 in vehicle and CNO, respectively; retest versus test, p > 0.05, Bonferroni’s multiple comparisons test. Data represent mean ± SEM.