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. 2023 Jan 19;13:67. doi: 10.1038/s41598-022-24529-3

Table 1.

Codon positions under positive selection detected by the site model using FUBAR and MEME using genes trees.

Gene Site model Branch-site model
FUBAR MEME codeML aBSREL
GHSR 211 (0.93) 243(0.03); 249(0.04) 211 (0.984) 0;34%
IGF2 0 0 0 0
IGFBP2 0 0 0 0
IGFBP7 0 0 278 (0.974)
EGF 0 0 0 0
LCORL 0 0 0 0
PLAG1 0 0 0 0
ZFAT 0 0 0 0
NCPAG 348 (0.91), 373 (0.95); 464 (0.95), 466 (0.94), 630 (0.97); 885 (0.93); 906 (0.95); 908 (0.94); 925 (0.92); 940 (0.93); 953 (0.94); 969 (0.92); 991 (0.93) 241 (0.03); 466 (0.03); 885 (0.04) 134 (0.953); 353 (0.950) 0

Significance was assessed by Posterior Probability (PP) > 90% in FUBAR and p value < 0.05 in MEME. Detection of the position of codons under positive selection was carried out through the branch-site model using codeML and aBSREL. Significance is obtained through BEB (Posterior Probability (PP) > 0.90) for codeML and p-value < 0.05 in aBSREL.