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. 2022 Dec 14;10(1):18–31. doi: 10.1002/acn3.51695

Figure 1.

Figure 1

Plasma p‐tau181 level as a binary classifier of disease status. Panels on the left (A, C, E) show the distribution of plasma p‐tau181 values among disease group or cognitively normal individuals. Black bars are inserted to show median and interquartile range. Panels on the right (B, D, F) show receiver operator characteristics (ROC) curves showing the area under the curve (AUC) of each disease group compared to cognitively normal individuals without evidence of amyloid deposition on PET imaging. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001. ns, non‐significant; PET, Amyloid positron emission tomography; MCI, Mild cognitive impairment; bvFTD, behavioral variant frontotemporal dementia; PPA, primary progressive aphasia; PD, cognitively normal Parkinson's disease; PSP, progressive supranuclear palsy; CBS, corticobasal syndrome; DLB, dementia with Lewy bodies; ALS, amyotrophic lateral sclerosis.