Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Principal effects of gingipain-R observed on HGF
| mRNA or protein | Effect of culture conditiona
|
|||
|---|---|---|---|---|
| Gingipain-R | T-cell contact | Gingipain-R + T-cell contact | Gingipain-R + T-cell contact + indomethacin | |
| COX-2 mRNA | + | + | + | ND |
| PGE2 | + | + | ++ | − |
| IL-8 | + | + | ++ | ± |
| IP-10 | No effect | + | ± | ND |
+, enhancement; ++, marked enhancement; −, inhibition; ±, decrease; ND, not done.
