Table 3.
Hazard Ratios (HR) from survival analyses investigating the effect of the Polygenic Score (PGS) for general musicality on registry-based mental health diagnoses and standardized beta coefficients (β) and p-values from linear regression analyses investigating the effect of PGS music on self-reported depressive and psychotic-like experiences.
| Registry-based diagnosis of | Self-reported | |||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Depression | Anxiety | Schizophrenia | Bipolar | Stress-related | Depressive symptoms | Psychotic-like experiences | Neuroticism | |||||||||||
| Ndiagnosed | 491 | 396 | 21 | 73 | 330 | 4,414 | 3,831 | 5,230 | ||||||||||
| Polygenic score | HR | P-value | HR | P-value | HR | P-value | HR | P-value | HR | P-value | β | P-value | β | P-value | β | P-value | ||
| Music | 1.10* | 0.04 | 1.05 | 0.34 | 0.86 | 0.51 | 1.06 | 0.64 | 0.95 | 0.41 | −0.01 | 0.71 | 0.00 | 0.83 | −0.01 | 0.38 | ||
| Sensitivity analyses | ||||||||||||||||||
| Music | 1.15* | 0.03 | 1.05 | 0.48 | 0.96 | 0.88 | 1.18 | 0.35 | 1.07 | 0.44 | −0.01 | 0.53 | 0.00 | 0.74 | −0.01 | 0.41 | ||
**Adjusted p-value < 0.016, *p-value < 0.05.
Number of cases receiving the diagnoses or sample sizes are reported at the top.
The lower part of the table displays the results of the sensitivity analyses including amount of lifetime music practice as a covariate. Significant effects in bold.