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. 2023 Jan 19;13:1023. doi: 10.1038/s41598-023-27706-0

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© The Author(s) 2023, corrected publication 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Transcriptome profiling of intestinal tissues in response to ATCC25526 or UMB-MBP-01. (A) Quadrant plot to show whether differential expressed genes (DEGs) have the same or opposite relationships between each of the pairwise comparison of UMB-MBP-001 vs control and UMB-MBP-001 vs ATCC25526. DEGs were determined using log2 fold change (LFC) > (+ /−)1 and false discovery rate (FDR) < 0.05. (B) Gene-Concept network for most over-represented Gene Ontology (GO) terms to depict over-represented functions based on q-value and gene-count. Over-representation analyses¹⁰⁶ of DEGs that are only different abundant in UMB-MBP-001 vs control but not in ATCC25526 vs control, using GO ontologies performed using enrichGO function of clusterProfile Bioconductor package¹⁰⁷. For pairwise comparison enrichment analyses for any two conditions, please refer to Supplemental Fig. 4.