Observed proportion of liver transplants in patients that did undergo siEHC during follow-up.
Genotypic categorization of BSEP1/1, BSEP1/3 and BSEP3/3 groups is defined in the methods section. Median age at siEHC was 2.9 years in BSEP1/1, 1.8 years in BSEP1/3 and 2.5 years in BSEP3/3. Log-rank tests. BSEP, bile salt export pump; siEHC, surgical interruption of the enterohepatic circulation.