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. 2023 Jan 5;9(1):e12829. doi: 10.1016/j.heliyon.2023.e12829

Table 2.

Total bioavailability of curcumin and its conjugates after a single oral administration of the test product vs. the reference product.

Constituent AUC0-T Test product AUC0-T Reference product F%
(nmol·hr/mL ± SEM) (nmol·hr/mL ± SEM)
Curcumin 0.0045 ± 0.0013 n/a
Curcumin sulfate 7.2657 ± 2.1907 0.4078 ± 0.1177 17,817
Curcumin glucuronide 0.0552 ± 0.0166 0.0045 ± 0.0013 12,267
TOTAL 7.3254 0.4123 17,767

Notes: F% = (Total AUC0-T test product/Total AUC0-T reference product) x 100.

Abbreviations: F%, percent bioavailability; AUC area under the curve.