Table 2.
Total bioavailability of curcumin and its conjugates after a single oral administration of the test product vs. the reference product.
Constituent | AUC0-T Test product | AUC0-T Reference product | F% |
---|---|---|---|
(nmol·hr/mL ± SEM) | (nmol·hr/mL ± SEM) | ||
Curcumin | 0.0045 ± 0.0013 | n/a | – |
Curcumin sulfate | 7.2657 ± 2.1907 | 0.4078 ± 0.1177 | 17,817 |
Curcumin glucuronide | 0.0552 ± 0.0166 | 0.0045 ± 0.0013 | 12,267 |
TOTAL | 7.3254 | 0.4123 | 17,767 |
Notes: F% = (Total AUC0-T test product/Total AUC0-T reference product) x 100.
Abbreviations: F%, percent bioavailability; AUC area under the curve.