TABLE 2.
Lymphoproliferative responses to B. pertussis antigens in DTaP-HBV recipients and in children with a previous diagnosis of pertussis by percentages of responders and magnitudes of proliferation
| Antigen | PBMC proliferation (cpm, 103) in:
|
|||
|---|---|---|---|---|
| DTaP-HBV recipients (n = 34)
|
Children in pertussis group (n = 14)
|
|||
| No. of responders (%) | Median (range) | No. of responders (%) | Median (range) | |
| PHA | 34 (100.0) | 82,296 (29,867–29,1100) | 14 (100.0) | 72,419 (34,798–27,1496) |
| PT | 5 (14.7) | 1,957 (243–73,156) | 1 (7.1) | 1,256 (373–17,747) |
| FHA | 6 (17.6) | 2,326 (260–50,862) | 2 (14.3) | 2,274 (331–44,389) |
| PRN | 6 (17.6) | 16,456* (251–103,136) | 2 (14.3) | 2,449* (297–19,913) |
a
Median values were calculated between antigen-stimulated and unstimulated cultures. P values were calculated using the χ2 test with Yates correction or Fisher's exact test and the Mann-Whitney U test, as appropriate. *, for values for DTaP-HBV recipients versus those for children in the pertussis group, P = 0.011.