TABLE 4.
Spearman’s rho coefficients between differences in CpGs and psychological measures.
| Cognitive measures N=(39 MZ twin pairs) | Laboratory-induced aggression N=(42 MZ twin pairs) | Personality measures N = (28 MZ twin pairs) | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Punishment intensity | Punishment duration | ||||||||||||||||
| DNAm difference (%) | Percent conceptual level responses | Perseverative errors | Non-perseverative errors | Failures to maintain set | Block 1 = no provocation | Block 2 = low provocation | Block 3 = mild provocation | Block 4 = high provocation | Block 1 = no provocation | Block 2 = low provocation | Block 3 = mild provocation | Block 4 = high provocation | BIS | BAS | Fight | Flight | Freeze |
| CpG1 | 0.08 | −0.02 | 0.35* | 0.44** | 0.38* | 0.17 | 0.10 | 0.12 | 0.06 | −0.03 | 0.03 | 0.12 | 0.07 | 0.08 | 0.34 | −0.16 | 0.27 |
| CpG2 | 0.18 | −0.15 | 0.13 | 0.22 | 0.12 | −0.13 | −0.01 | −0.01 | −0.01 | −0.17 | 0.07 | 0.10 | 0.27 | 0.11 | 0.34 | −0.02 | 0.52** |
| CpG3 | 0.24 | −0.23 | 0.25 | 0.30 | 0.39* | 0.08 | −0.23 | −0.11 | 0.19 | 0.02 | −0.07 | 0.03 | 0.30 | −0.10 | 0.36 | 0.10 | 0.44* |
| CpG4 | 0.11 | −0.04 | 0.18 | 0.17 | 0.27 | 0.05 | 0.07 | 0.13 | 0.11 | −0.06 | 0.06 | 0.22 | 0.15 | −0.17 | 0.39* | −0.18 | 0.50** |
| CpG5 | −0.14 | −0.18 | 0.13 | 0.16 | 0.16 | 0.08 | −0.01 | 0.10 | −0.06 | −0.01 | 0.09 | 0.14 | −0.08 | 0.21 | 0.02 | −0.28 | 0.34 |
| Mean CpG+ | 0.06 | −0.12 | 0.24 | 0.17 | 0.30 | −0.01 | −0.13 | −0.10 | 0.15 | −0.10 | −0.02 | 0.05 | 0.02 | −0.04 | 0.28 | −0.15 | 0.27 |
Note. Mean CPG+, mean of CpG1-5 sites; BIS, Behavioral Inhibition System; BAS, Behavioral Activation System. Bolded correlations remained significant after Bonferroni p-adjustment. *p < 0.05. **p < 0.01.