TABLE 1.

ZFNs and TALENs for nutritional and phenotype improvement in cereals.

Crop	Gene editor	Gene targeted	Improvement	Method	References
Rice (Oryza sativa)	ZFNs	OsQQR	Trait stacking	HDR	Cantos et al. (2014)
	TALEN	OsDEP1, OsBADH2, OsCKX2, and OsSD1	Gene knockout	NHEJ	Shan et al. (2013)
	TALEN	OsBADH2	Fragrant rice	NHEJ	Shan et al. (2015)
	1.1.1 TALEN	OsMST7 and OsMST8	Gene knockout	NHEJ	Zhang et al. (2016)
	TALEN	Os11N3 (OsSWEET14)	Disease resistance	NHEJ	Li et al. (2012)
Maize (Zea mays)	ZFNs	ZmIPK1	Herbicide tolerant and phytate-reduced maize	HDR	Shukla et al. (2009)
	ZFNs	ZmTLP	Trait stacking	HDR	Ainley et al. (2013)
	TALEN	ZmMTL	Induction of haploid plants	NHEJ	Kelliher et al. (2017)
	TALEN	ZmIPK1A, ZmIPK, and ZmMRP4	Phytic acid synthesis	NHEJ	Liang et al. (2014)
	TALEN	ZmGL2	Reduced epicuticular wax in leaves	NHEJ	Char et al. (2015)
Barley (Hordeum vulgare)	TALEN	HvPAPhy-a	Phytase activity	NHEJ	Wendt et al. (2013)
	TALEN	BAR	Bialaphos resistance	__	Gurushidze et al. (2014)