TABLE 3.
List of genes targeted by cytidine and adenine base editors in cereal crops.
| Cereal plant species | Trait improvement | Type of base editor used | Target gene | References(s) |
|---|---|---|---|---|
| Rice (Oryza sativa) | Nitrogen use efficiency | CBE | NRT1.1B and SLR1 | Lu and Zhu (2017) |
| Senescence and death | CBE | OsCDC48 | Zong et al. (2017) | |
| Nutritional improvement | CBE | OsPDS and OsSBEIIb | Li et al. (2017) | |
| Herbicide resistant | CBE | C287 | Shimatani et al. (2017) | |
| Pathogen-responsive gene | ABE | OsMPK6 | Yan et al. (2018) | |
| Defense response | CBE | OsRLCK185 and OsCERK1 | Ren et al. (2018) | |
| Plant architecture and grain yield | ABE | OsSPL14 | Hua et al. (2018) | |
| Herbicide resistance | ABE | OsACC-T1 | Li et al. (2018) | |
| Della protein for plant height | ABE | SLR1 | Hua et al. (2018) | |
| Herbicide resistance | CBE | OsSPL14 | Tian et al. (2018) | |
| Blast resistance | CBE | Pi-d2 | Ren et al. (2018) | |
| Herbicide resistance | CBE | ALS | Veillet et al. (2019) | |
| Grain size and yield | ABE | GL2/OsGRF4 and OsGRF3 | Hao et al. (2019) | |
| Rice amylose synthesis | ABE | Wx | Hao et al. (2019) | |
| Wheat (Triticum aestivum) | Panicle length and grain weight | ABE | TaDEP1 and TaGW2 | Li et al. (2020) |
| Lipid metabolism | CBE | TaLOX2 | Zong et al. (2017) | |
| Maize (Zea mays) | Chromosomal segregation | CBE | ZmCENH3 | Zong et al. (2017) |