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. 2023 Jan 6;13:866976. doi: 10.3389/fgene.2022.866976

TABLE 3.

List of genes targeted by cytidine and adenine base editors in cereal crops.

Cereal plant species Trait improvement Type of base editor used Target gene References(s)
Rice (Oryza sativa) Nitrogen use efficiency CBE NRT1.1B and SLR1 Lu and Zhu (2017)
Senescence and death CBE OsCDC48 Zong et al. (2017)
Nutritional improvement CBE OsPDS and OsSBEIIb Li et al. (2017)
Herbicide resistant CBE C287 Shimatani et al. (2017)
Pathogen-responsive gene ABE OsMPK6 Yan et al. (2018)
Defense response CBE OsRLCK185 and OsCERK1 Ren et al. (2018)
Plant architecture and grain yield ABE OsSPL14 Hua et al. (2018)
Herbicide resistance ABE OsACC-T1 Li et al. (2018)
Della protein for plant height ABE SLR1 Hua et al. (2018)
Herbicide resistance CBE OsSPL14 Tian et al. (2018)
Blast resistance CBE Pi-d2 Ren et al. (2018)
Herbicide resistance CBE ALS Veillet et al. (2019)
Grain size and yield ABE GL2/OsGRF4 and OsGRF3 Hao et al. (2019)
Rice amylose synthesis ABE Wx Hao et al. (2019)
Wheat (Triticum aestivum) Panicle length and grain weight ABE TaDEP1 and TaGW2 Li et al. (2020)
Lipid metabolism CBE TaLOX2 Zong et al. (2017)
Maize (Zea mays) Chromosomal segregation CBE ZmCENH3 Zong et al. (2017)