TABLE 2.

Effects induced by fecal matter transplantations from animals treated with resveratrol on gut microbiota composition.

References	Experimental design	Main results concerning glycaemic control	Main results concerning microbiota
Sung et al. (30)	Animals: non-germ free C57Bl/6J mice Age and sex: 8-week-old; male Diets: high-fat high-sucrose diet (45% of energy from fat and 17% from sucrose) Faecal transplantation: from mice fed a standard diet or from mice fed the high-fat high-sucrose diet supplemented with 0.4% of resveratrol Experimental period length: 8 weeks (last 2 weeks of transplantation)	Transplantation from mice fed resveratrol: Improvement in glucose clearance	↑ Parabacteroides ↓ Proteobacteria ↓ Moryella ↓ Akkermansia
Kim et al. (37)	Animals: C57Bl/6J mice Age and sex: 8-week-old; male Diets: high-fat high-sucrose diet (45% of energy from fat and 17% from sucrose) Faecal transplantation: from mice fed a standard diet or from mice fed the high-fat high-sucrose diet supplemented with 0.4% of resveratrol Experimental period length: 8 weeks (last 2 weeks of transplantation)	Transplantation from mice fed resveratrol: ↓ Fasting serum glucose levels No effect on insulin levels.	Not analysed
Wang et al. (31)	Animals: C57BL/6J mice Age and sex: 6-week-old; male Diets: high-fat diet (60% of energy from fat) Faecal transplantation: from mice fed a standard diet supplemented or not with resveratrol or a high-fat high-sucrose diet supplemented with resveratrol (300 mg/kg BW/d) Experimental period length: 18 weeks (last 16 weeks of transplantation)	Transplantation from mice fed resveratrol and the high-fat diet: ↓ Fasting blood insulin No effect on fasting glucose levels Transplantation from mice fed resveratrol and standard diet: ↓ Fasting blood glucose ↓ Fasting blood glucose insulin Improved glucose and insulin response	↑Allobaculum ↑ Bacteroides ↑ Alistipes ↓ Desulfovibrio

BW, body weight.