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. 2023 Jan 6;9:1050310. doi: 10.3389/fcvm.2022.1050310

TABLE 2.

Baseline characteristics of patients from whom aortic valves were obtained.

All patients (n = 23) non-AS (n = 12) AS (n = 11) p-value
Age, years 66 ± 8 61 ± 7 71 ± 5 <0.001
Male, n (%) 20 (87.0%) 10 (83.3%) 10 (90.9%) 1.000
BMI, kg/m2 21.41 ± 1.80 22.24 ± 1.93 20.51 ± 1.17 0.018
Drinking, n (%) 4 (17.4%) 1 (8.3%) 3 (27.3%) 0.317
Smoking, n (%) 5 (21.7%) 2 (16.7%) 3 (27.3%) 0.640
Hypertension, n (%) 15 (65.2%) 8 (66.7%) 7 (63.6%) 1.000
CAD, n (%) 23 (100.0%) 12 (100.0%) 11 (100.0%) 1.000
DM, n (%) 3 (13.0%) 3 (25.0%) 0 (0.0%) 0.217
HbA1c,% 5.78 ± 0.54 6.00 ± 0.47 5.52 ± 0.52 0.030
Fasting glucose, mmol/L 5.25 ± 0.61 5.30 ± 0.82 5.20 ± 0.28 0.684
TG, mmol/L 1.26 (0.90–1.60) 1.40 (0.94–2.06) 1.15 (0.89–1.35) 0.347
TC, mmol/L 4.45 ± 1.06 4.32 ± 0.92 4.59 ± 1.23 0.542
HDL-C, mmol/L 1.00 ± 0.12 0.95 ± 0.13 1.06 ± 0.09 0.036
LDL-C, mmol/L 2.82 ± 0.80 2.82 ± 0.78 2.83 ± 0.85 0.975
Lp (a), g/L 0.11 (0.05–0.49) 0.07 (0.04–0.63) 0.20 (0.07–0.39) 0.26
BUN, mmol/L 6.10 (5.00–7.70) 6.15 (4.68–7.38) 6.10 (5.60–8.40) 0.608
Scr, μmol/L 80.39 ± 22.94 86.83 ± 25.07 73.36 ± 19.02 0.164
eGFR, mL/min/1.73 m2 84.15 ± 17.76 83.27 ± 22.03 85.12 ± 12.56 0.809
γ-GT, IU/L 30.48 ± 12.46 32.17 ± 14.28 28.64 ± 10.51 0.510
Ca, mmol/L 2.25 ± 0.13 2.24 ± 0.16 2.26 ± 0.08 0.793
P, mmol/L 1.07 ± 0.24 1.18 ± 0.16 0.94 ± 0.27 0.017
Statins, n (%) 5 (21.7%) 4 (33.3%) 1 (9.1%) 0.317
Antidiabetic therapy, n (%) 3 (13.0%) 3 (25.0%) 0 (0.0%) 0.217

Normally distributed variables: mean ± SD; skewed variables: median (interquartile range); categorical variable: n (%). For continuous variables, independent Student’s t-tests and Mann-Whitney U-tests were performed to assess differences. Differences in proportions were analyzed by 2 × 2 chi-square tests. Abbreviations as in Table 1.