TABLE 3.
Factors correlated with 3-month, and 6-month mortality in multivariate analyses in patients with decompensated liver cirrhosis in the development cohort and validation cohort.
| Variables | Development cohort | Validation cohort | ||||||
| 3 months OR (95% CI) | P | 6 months OR (95% CI) | P | 3 months OR (95% CI) | P | 6 months OR (95% CI) | P | |
| WBC (109/L) | 1.098 (0.935–1.280) | 0.230 | 1.107 (0.957–1.279) | 0.160 | 1.173 (0.951–1.469) | 0.138 | 1.203 (0.994–1.486) | 0.065 |
| PLT (109/L) | 1.005 (1.000–1.011) | 0.044 | 1.005 (1.000–1.010) | 0.072 | 1.005 (0.990–1.020) | 0.469 | 0.999 (0.983–1.012) | 0.837 |
| AST (U/L) | 1.002 (0.998–1.005) | 0.349 | 0.990 (0.970–1.004) | 0.238 | ||||
| BUN (mmol/L) | 1.086 (0.981–1.212) | 0.122 | 1.087 (0.961–1.218) | 0.160 | ||||
| PT (S) | 1.057 (0.843–1.329) | 0.628 | 1.045 (0.868–1.261) | 0.639 | 0.963 (0.757–1.152) | 0.670 | 1.120 (0.945–1.408) | 0.256 |
| MELD score | 1.059 (0.905–1.237) | 0.469 | 1.076 (0.950–1.213) | 0.232 | 1.167 (0.977–1.411) | 0.095 | 1.057 (0.917–1.214) | 0.430 |
| PNI | 0.037 | 0.006 | 0.036 | 0.006 | ||||
| Low | Reference | Reference | Reference | Reference | ||||
| High | 0.187 (0.028–0.756) | 0.162 (0.036–0.530) | 0.098 (0.005–0.592) | 0.053 (0.003–0.283) | ||||
WBC, white blood cell; PLT, platelet; AST, aspartate aminotransferase; BUN, blood urea nitrogen; PT, prothrombin time; MELD, Model for End-Stage Liver Disease; PNI, prognostic nutritional index; OR, odds ratio; CI, confidence interval. Age, sex, hemoglobin, WBC, PLT, AST, BUN, PT, PNI, MELD score, total bilirubin, alanine aminotransferase, γ–glutamyl transpeptidase, and creatinine were included in the univariate logistic regression analysis. Variables that did not have a significant effect on mortality in the univariate logistic regression analysis were not included in the multivariate logistic regression analysis.