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. 2023 Jan 6;9:1021899. doi: 10.3389/fmed.2022.1021899

Table 2.

Comparison of demographics, clinical and laboratory data between the non-PVT group and PVT group in the training set.

Variable non-PVT PVT P
n = 3,157 n = 203
Age (year) 55 (47–64) 56 (50–64) 0.086
Sex (male/female) 2,172/985 143/60 0.624
Smoking history 261 (8.3%) 42 (20.7%) <0.001
Cause of admission 0.003
  Gastrointestinal bleeding 401 (12.7%) 43 (21.2%)
  Ascites 628 (19.9%) 43 (21.2%)
  Jaundice 272 (8.6%) 11 (5.4%)
  Dysfunction of liver 171 (5.4%) 8 (3.9%)
  Infection 781 (24.7%) 53 (26.1%)
  Abdominal discomfort 715 (22.6%) 30 (14.8%)
  Other 189 (6.0%) 15 (7.4%)
Etiology 0.763
  Hepatitis 1,965 (62.2%) 131 (64.5%)
  Alcoholic 673 (21.3%) 44 (21.7%)
  Autoimmune 91 (2.9%) 4 (2.0%)
  Other 428 (13.6%) 24 (11.8%)
Complications
  Splenomegaly 2,012 (63.7%) 165 (81.3%) <0.001
  Portal_hypertension 1,281 (40.6%) 129 (63.5%) <0.001
  Esophagogastric varices 1,023 (32.4%) 116 (57.1%) <0.001
  Gastrointestinal_bleeding 449 (14.2%) 47 (23.2%) 0.001
  Ascites 1,081 (34.2%) 79 (38.9%) 0.174
  Encephalopathy 163 (5.2%) 17 (8.4%) 0.049
Comorbidities
  Hypertension 504 (16.0%) 29 (14.3%) 0.526
  Diabetes 469 (14.9%) 40 (19.7%) 0.062
  Heart disease 173 (5.5%) 9 (4.4%) 0.523
  Renal failure 21 (0.7%) 1 (0.5%) 0.768
  Surgical history 307 (9.7%) 46 (22.7%) <0.001
  Sepsis 59 (1.9%) 2 (1.0%) 0.361
Child-pugh classification 0.416
  A 1,088 (34.5%) 61 (30.0%)
  B 1,402 (44.4%) 98 (48.3%)
  C 667 (21.1%) 44 (21.7%)
RBC transfusion 264 (8.4%) 38 (18.7%) <0.001
WBC (× 109/L) 4.91 (3.47–6.88) 4.38 (3.09–6.50) 0.040
Hb (g/L) 111 (90–127) 100 (80–116) <0.001
HCT (%) 33.3 (27.6–38.3) 31.1 (25.3–35.1) <0.001
PLT (× 109/L) 97 (60–151) 91 (49–145) 0.114
PT (s) 13.5 (11.9–16.0) 13.9 (12.3–16.6) 0.044
INR 1.18 (1.04–1.38) 1.21 (1.08–1.44) 0.036
APTT (s) 38.0 (31.4–47.3) 39.1 (31.0–49.3) 0.473
DDi (mg/L) 1.03 (0.40–2.77) 1.76 (0.54–4.73) <0.001
TB (μmol/L) 27.7 (16.7–58.5) 27.4 (16.9–46.4) 0.645
ALB (g/L) 31.5 (27.4–35.8) 29.6 (25.9–34.6) 0.003
ALT (U/L) 43.1 (24.1–91.4) 29.5 (19.1–52.3) <0.001
AST (U/L) 61.0 (34.6–117.5) 42.6 (28.9–82.4) <0.001

RBC transfusion, red blood cell transfusion; WBC, white blood cell count; Hb, hemoglobin; Hct, Hematokrit; PT, prothrombin time; APTT, activated partial thromboplastin time; INR, international normalized ratio; DDi, D-dimer; TB, total bilirubin; ALB, albumin; ALT, alanine transaminase; AST, aspartate aminotransferase.