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The antiproliferative activity of compound 3-7 combined with 5-FU against colorectal cancer cells.
| Compounds | IC50 (μM) for 48 h | |
|---|---|---|
| HCT-8 | LoVo | |
| 5-FU | 8.47 | 19.3 |
| 3 + 5-FU | 3.94 | 10.40 |
| 4 + 5-FU | 5.09 | 15.99 |
| 5 + 5-FU | 9.13 | 12.15 |
| 6 + 5-FU | 8.55 | 5.20 |
| 7 + 5-FU | 8.33 | 17.09 |
