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Some of the anti-lactate drugs that have been reported.
| Type | Inhibitors | Targets | Reference |
|---|---|---|---|
| glycolysis | 2-DG | HK2 | (212, 213) |
| glycolysis | 3-BrPA | HK2 | (214–216) |
| lactate production | Oxamate | LDHA | (217) |
| lactate production | Quinoline-3-sulfonamides | LDHA/LDHB | (218) |
| lactate production | Galloflavin | LDHA | (219) |
| lactate transport | AZD3965 | MCT1 | (220) |
| lactate transport | AR-C155858 | MCT1 | (221) |
| lactate transport | BAY-8002 | MCT1 | (222) |
| lactate transport | Lonidamine | MCT1/4 | (223–225) |
| lactate transport | VB124 | MCT1 | (226) |
