Table 1.

Definitions of key implementation outcomes and modifications.

FRAME-IS coding definitions (32)
What is modified?	Content, Training, Evaluation: changes in the subject matter of a strategy or the way implementers are trained or the way a strategy is evaluated
	Context: changes to the format, setting, personnel, or population of a strategy
What is the nature of the modification?	Adding, removing, substituting, repeating, etc.
Is it fidelity consistent or inconsistent?	Do the changes reflect a preservation or alteration of core elements
What is the goal?	Reach: is the strategy reaching the intended population
	Adoption: is the intended population using the strategy
	Acceptability/appropriateness: is the strategy perceived as fitting, relevant, or compatible
	Fidelity: extent to which implemented as intended
	Sustainability: is the strategy integrated into routine practice
What is the level of the rational for modification?	Micro: recipient or implementer
	Meso: organizational
	Macro: sociopolitical
When is the modification initiated?	Pre-implementation, implementation, scale up, maintenance, sustainment
Is the modification planned or proactive?	Planned and proactive: adaptation
	Planned and reactive: adaptation
	Unplanned and reactive: modification
Who participates in the decision? Who makes the ultimate decision?	Recipient, implementer, implementation support, funder, manager, leader
How widespread is the modification?	Individual recipient, group of recipients, individual implementer, group of implementers, organization, network