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. 2023 Jan 6;10:1038435. doi: 10.3389/fpubh.2022.1038435

Table 3.

The associations of dietary fiber consumption with liver function parameters.

Liver function parametersa Dietary fiber consumption Per 1-SD Ptrendd
Tertile 1 Tertile 2 Tertile 3
Albumin
Model 1b 0 0.62 (−0.02 to 1.25) 1.36 (0.72 to 2.00) 0.58 (0.33 to 0.84) <0.001
Model 2c 0 1.08 (0.46 to 1.71) 2.00 (1.33 to 2.67) 0.84 (0.56 to 1.12) <0.001
Globulin
Model 1b 0 −1.67 (−2.71 to −0.62) −0.68 (−1.73 to 0.38) −0.25 (−0.69 to 0.18) 0.253
Model 2c 0 −1.61 (−2.68 to −0.53) −1.53 (−2.66 to −0.40) −0.74 (−1.21 to −0.26) 0.003
Total protein
Model 1b 0 −0.41 (−0.88 to 0.06) 0.42 (−0.05 to 0.90) 0.20 (0.01 to 0.39) 0.044
Model 2c 0 −0.13 (−0.61 to 0.36) 0.42 (−0.10 to 0.94) 0.14 (−0.07 to 0.36) 0.198
Total bilirubin
Model 1b 0 8.65 (4.22 to 13.27) 7.39 (3.02 to 11.95) 2.25 (0.52 to 4.00) 0.011
Model 2c 0 8.63 (3.99 to 13.47) 6.20 (1.43 to 11.20) 1.53 (−0.40 to 3.50) 0.121
ALT
Model 1b 0 1.19 (−2.97 to 5.52) 2.38 (−1.82 to 6.76) 1.29 (−0.43 to 3.04) 0.143
Model 2c 0 0.82 (−3.38 to 5.20) −0.08 (−4.46 to 4.50) 0.88 (−0.99 to 2.79) 0.360
AST
Model 1b 0 1.42 (−1.34 to 4.27) 2.35 (−0.44 to 5.21) 1.05 (−0.08 to 2.20) 0.069
Model 2c 0 0.64 (−2.29 to 3.66) 0.80 (−2.29 to 3.98) 0.65 (−0.65 to 1.96) 0.331
GGT
Model 1b 0 −2.55 (−7.45 to 2.61) −7.84 (−12.47 to −2.97) −3.83 (−5.84 to −1.78) <0.001
Model 2c 0 −2.45 (−7.44 to 2.82) −9.80 (−14.66 to −4.66) −4.22 (−6.43 to −1.96) <0.001

ALT, alanine aminotransferase; AST, aspartate aminotransferase; GGT, gamma-glutamyl transaminase.

a

Liver function parameters were natural logarithm transformed. Percentage change (%) and 95% confidence intervals were calculated as (eβ – 1)*100% based on multivariable linear regression.

b

Model 1 did not adjust for the covariates.

c

Model 2 was adjusted for age, sex, smoking, race/ethnicity, education, ratio of family income to poverty, physical activity, total energy, hypertension, and diabetes.

dThe trend test was performed by using z-score in the models.