TABLE 6.

Increases in normalized stool IgA titers specific for S. flexneri 2a LPS

Time (day or peak)	Results for different doses (mg)
	0.1		0.4		1.0		1.5
	Geometric mean fold rise	% >2-fold risef	Geometric mean fold rise	% >2-fold rise	Geometric mean fold rise	% >2-fold rise	Geometric mean fold rise	% >2-fold rise
14	1.07	20	1.19a	11a	1.42	50	1.48	40
23	0.80	20	1.62a	33a	2.11	60	0.71b	17b
42	0.70	0	0.85a	10a	1.03	20	1.13	30
70	0.65	0	1.10	10	1.59c	50	1.48d	40
Peake	1.35	20	2.07	33	3.36	70	2.37	70

^aSubjects were evaluable. 

^bOnly six subjects were evaluable. 

^cP = 0.10 for the comparison of the geometric mean fold rise to 1, i.e., no change. 

^dP < 0.06 for the comparison of the geometric mean fold rise to 1, i.e., no change. 

^eIncludes the strongest response for each subject with at least three postimmunization values. 

^fPercentage by which result exceeds twofold increase is given.