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Sunitinib promotes apoptosis in 143B osteosarcoma cells with decreased expression of KCNJ3. (A) 143B osteosarcoma cell viability evaluation via CCK-8 assay. (B,C) The expression level of KCNJ3 protein. (D,E) The protein expression levels of Bcl-2, Bax, and caspase3. All experiments were repeated in triplicates (n = 3). The obtained data are represented as mean ± SE. Significance: @@@ p-value < .001, vs. sham (0 μM) group. # p-value < .05, ## p-value < .01, ### p-value < .001.
