Table 9.
Studies published on Blastomycosis in Africa.
| Country | Clinical Type | Number of Cases | Affected site | Aetiology | Diagnostic Tool | Treatment | Outcomes | Year | Authors |
|---|---|---|---|---|---|---|---|---|---|
| South Africa |
Cutaneous (n = 4), Subcutaneous (n = 1), Pulmonary (n = 3), Vertebral (n = 1), Multisystem (n = 6) | 20 (1967–2014) |
- | B. persursus, B. emzantsi | Histopathology, Culture, Microscopy, PCR |
Voriconazole, posaconazole, itraconazole, amphotericin B and micafungin | Death (n = 5), Favourable (n = 5), Unknown (n = 10) |
2020 | Maphanga et al. [198] |
| Tunisia | Pulmonary, Subcutaneous disease | 1 | Right and left Lungs, Left paravertebral swelling around T10 |
B. dermatitidis | Culture, Radiology |
Itraconazole | Favourable | 2020 | Abdallah et al. [194] |
| South Africa | Cutaneous disease | 1 | Scalp, Face, Neck | B. dermatitidis | Histopathology, Culture |
Itraconazole | Favourable | 2012 | Motswaledi et al. [200] |
| Morocco | Pulmonary, Vertebral disease | 1 | Left lung, Vertebra | B. dermatitidis | Radiology, Histopathology |
Ketoconazole | Favourable | 2012 | Rais et al. [204] |
| Tunisia | Cutaneous disease | 2 | Right leg (patient 1), Left knee and Left shoulder (patient 2) |
B. dermatitidis | Histopathology, Culture |
- | - | 2004 | El Euch et al. [199] |
| Tunisia | Cutaneous disease | 1 | Right leg | B. dematitis | Histopathology, Enzyme linked immunosorbent assay |
Itraconazole | Favourable | 2017 | Ben Salem et al. [201] |
| Tunisia | Cutaneous disease | 3 | Right cheek (patient 1), Left cheek (Patient 2), Right iliac fossa |
- | Histopathology, Culture |
Ketoconazole | Favourable | 2006 | Ferchichi et al. [202] |
| Tunisia | Pulmonary, Vertebral disease | 1 | Right lower limb, Right lung |
B. dermatitidis | Histopathology, Culture, Radiology |
Itraconazole | Favourable | 2008 | Cheikh Rouhou et al. [205] |
| Tanzania | Pulmonary, Cutaneous disease | 1 | Lung, Nose, Right hand and right forearm, Left buttock, Left upper arm | B. dermatitidis | Histopathology | Itraconazole | Favourable | 2006 | Alvarez et al. [206] |
| Nigeria | Pulmonary | 1 | Right Lung | B. dermatitidis | - | Ketoconazole | Favourable | 2001 | Ibrahim et al. [207] |
| Morocco | Cutaneous disease | 1 | Forearm | B. dermatitidis | Histopathology |
- | Death | 2007 | Harket et al. [203] |
| Uganda | Pulmonary, Cutaneous disease | 11 | Lower limbs (n = 7), Upper limbs (n = 1), Abdominal wall (n = 1) |
B. dermatitidis | Histopathology | - | - | 2020 | Kwizera at al [98] |