Table 2.

Gating properties of N-type (CaV2.2) calcium currents recorded on DRG neurons.^a

N-type Ca2+	DMSO	Compound 8	p value
Activation
V1/2	2.1 ± 0.6 (11)	2.2 ± 1.7 (8)	0.931
k	5.6 ± 0.6 (11)	8.2 ± 1.5 (8)	0.134
Inactivation
V1/2	−24.3 ± 2.4 (11)	−20.2 ± 3.6 (8)	0.37
k	−17.6 ± 2.5 (11)	−17.4 ± 3.5 (8)	0.966

^aValues are mean ± SEM calculated fitting the data from the indicated number of individual cells (in parentheses) to the Boltzmann equation: V_1/2 midpoint potential (mV) for voltage dependence of activation or inactivation; and k slope factor. These values correspond to data shown in Fig. 3. No statistical differences were observed between groups. Data were analyzed with t-test with Welch’s correction. Abbreviations: DRG, dorsal root ganglia: DMSO, dimethyl sulfoxide.