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. 2023 Jan 6;16:1014081. doi: 10.3389/fnins.2022.1014081

TABLE 5.

Result of PCR predicting the neurite dispersion index (NDI) quantified from the ipsilateral cortex ROI from the plasma amino acid panel at day sixty post-injury.

Dependent variable: NDI in the ipsilateral cortex ROI
Model
Analysis of variance SS DF MS F(DFn,DFd) P-value
Regression 1.06E−01 3 3.53E−02 F(3,3) = 54.13 P = 0.0182
Residual 1.30E−03 3 6.52E−04
Total 1.07E−01 6
Goodness of fit
DOF 3
Adjusted R squared 0.976
Day 60 plasma amino acids as variables Estimate 95% CI (asymptotic) |t| P−value
Intercept 7.90E−01 −2.54E−01 to 1.83E + 00 3.257 0.0827 ns
Histidine 4.06E−02 2.64E−02 to 5.47E−02 12.3 0.0065 **
Asparagine 6.11E−03 1.47E−03 to 1.07E−02 5.663 0.0298 *
Serine 1.06E−02 6.23E−03 to 1.50E−02 10.42 0.0091 **
Glutamine 4.60E−03 2.84E−03 to 6.37E−03 11.22 0.0078 **
Arginine −2.03E−02 −2.77E−02 to −1.28E−02 11.68 0.0073 **
Glycine 1.54E−03 −2.49E−03 to 5.57E−03 1.641 0.2424 ns
Aspartic acid 9.83E−04 −7.70E−03 to 9.67E−03 0.4867 0.6746 ns
Glutamic acid −5.86E−03 −9.32E−03 to −2.39E−03 7.275 0.0184 *
Threonine −6.18E−04 −2.56E−03 to 1.32E−03 1.373 0.3036 ns
Alanine 3.79E−03 2.29E−03 to 5.30E−03 10.87 0.0084 **
Proline 5.36E−03 2.89E−03 to 7.84E−03 9.314 0.0113 *
Lysine −7.29E−03 −9.81E−03 to −4.78E−03 12.47 0.0064 **
Tyrosine 8.19E−04 −6.20E−03 to 7.84E−03 0.5017 0.6657 ns
Methionine −2.51E−02 −4.25E−02 to −7.57E−03 6.166 0.0253 *
Valine −9.41E−04 −4.91E−03 to 3.03E−03 1.02 0.4151 ns
Isoleucine 1.80E−03 −4.58E−03 to 8.18E−03 1.212 0.3492 ns
Leucine −7.11E−03 −1.26E−02 to −1.61E−03 5.567 0.0308 *
Phenylalanine −5.13E−02 −7.43E−02 to −2.83E−02 9.582 0.0107 *
Tryptophan 2.70E−02 1.33E−02 to 4.08E−02 8.452 0.0137 *

ns, not significant, *P-value < 0.05, and **P-value < 0.01.