TABLE 5.
Result of PCR predicting the neurite dispersion index (NDI) quantified from the ipsilateral cortex ROI from the plasma amino acid panel at day sixty post-injury.
Dependent variable: NDI in the ipsilateral cortex ROI | |||||||
Model | |||||||
Analysis of variance | SS | DF | MS | F(DFn,DFd) | P-value | ||
Regression | 1.06E−01 | 3 | 3.53E−02 | F(3,3) = 54.13 | P = 0.0182 | ||
Residual | 1.30E−03 | 3 | 6.52E−04 | ||||
Total | 1.07E−01 | 6 | |||||
Goodness of fit | |||||||
DOF | 3 | ||||||
Adjusted R squared | 0.976 | ||||||
Day 60 plasma amino acids as variables | Estimate | 95% CI (asymptotic) | |t| | P−value | |||
Intercept | 7.90E−01 | −2.54E−01 | to | 1.83E + 00 | 3.257 | 0.0827 | ns |
Histidine | 4.06E−02 | 2.64E−02 | to | 5.47E−02 | 12.3 | 0.0065 | ** |
Asparagine | 6.11E−03 | 1.47E−03 | to | 1.07E−02 | 5.663 | 0.0298 | * |
Serine | 1.06E−02 | 6.23E−03 | to | 1.50E−02 | 10.42 | 0.0091 | ** |
Glutamine | 4.60E−03 | 2.84E−03 | to | 6.37E−03 | 11.22 | 0.0078 | ** |
Arginine | −2.03E−02 | −2.77E−02 | to | −1.28E−02 | 11.68 | 0.0073 | ** |
Glycine | 1.54E−03 | −2.49E−03 | to | 5.57E−03 | 1.641 | 0.2424 | ns |
Aspartic acid | 9.83E−04 | −7.70E−03 | to | 9.67E−03 | 0.4867 | 0.6746 | ns |
Glutamic acid | −5.86E−03 | −9.32E−03 | to | −2.39E−03 | 7.275 | 0.0184 | * |
Threonine | −6.18E−04 | −2.56E−03 | to | 1.32E−03 | 1.373 | 0.3036 | ns |
Alanine | 3.79E−03 | 2.29E−03 | to | 5.30E−03 | 10.87 | 0.0084 | ** |
Proline | 5.36E−03 | 2.89E−03 | to | 7.84E−03 | 9.314 | 0.0113 | * |
Lysine | −7.29E−03 | −9.81E−03 | to | −4.78E−03 | 12.47 | 0.0064 | ** |
Tyrosine | 8.19E−04 | −6.20E−03 | to | 7.84E−03 | 0.5017 | 0.6657 | ns |
Methionine | −2.51E−02 | −4.25E−02 | to | −7.57E−03 | 6.166 | 0.0253 | * |
Valine | −9.41E−04 | −4.91E−03 | to | 3.03E−03 | 1.02 | 0.4151 | ns |
Isoleucine | 1.80E−03 | −4.58E−03 | to | 8.18E−03 | 1.212 | 0.3492 | ns |
Leucine | −7.11E−03 | −1.26E−02 | to | −1.61E−03 | 5.567 | 0.0308 | * |
Phenylalanine | −5.13E−02 | −7.43E−02 | to | −2.83E−02 | 9.582 | 0.0107 | * |
Tryptophan | 2.70E−02 | 1.33E−02 | to | 4.08E−02 | 8.452 | 0.0137 | * |
ns, not significant, *P-value < 0.05, and **P-value < 0.01.