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. 2023 Jan 6;13:1098800. doi: 10.3389/fphar.2022.1098800

TABLE 2.

Predicted drugs with interactions with 17 key targets.

Pubchem_ID Drug_name Target_uniprot Target_gene Score
40839 Vindesine Q9C004 SPRY4 5.8344
13342 Vinblastine Q9C004 SPRY4 5.7434
5743 Dexamethasone Q9C004 SPRY4 5.7027
40839 Vindesine Q13950 RUNX2 5.8562
13342 Vinblastine Q13950 RUNX2 5.7793
5743 Dexamethasone Q13950 RUNX2 5.6826
40839 Vindesine P23470 PTPRG 5.7527
13342 Vinblastine P23470 PTPRG 5.6951
40839 Vindesine P09619 PDGFRB 7.3506
13342 Vinblastine P09619 PDGFRB 8.2389
5978 Vincristine P09619 PDGFRB 8.1492
5743 Dexamethasone P09619 PDGFRB 6.6296
40839 Vindesine Q99983 OMD 5.9503
13342 Vinblastine Q99983 OMD 5.934
5978 Vincristine Q99983 OMD 5.8099
5743 Dexamethasone Q99983 OMD 5.8695
40839 Vindesine P35968 KDR 7.5846
13342 Vinblastine P35968 KDR 7.92
5978 Vincristine P35968 KDR 7.9899
5743 Dexamethasone P35968 KDR 6.2217
3657 Hydroxyurea P05412 JUN 5.6947
40839 Vindesine P01583 IL1A 5.742
13342 Vinblastine P01583 IL1A 5.7095
40839 Vindesine P10144 GZMB 6.353
13342 Vinblastine P10144 GZMB 6.3015
5978 Vincristine P10144 GZMB 6.135
5743 Dexamethasone P10144 GZMB 6.1824
40839 Vindesine P17948 FLT1 7.5469
13342 Vinblastine P17948 FLT1 7.947
5978 Vincristine P17948 FLT1 8.0129
5743 Dexamethasone P17948 FLT1 6.5217
40839 Vindesine Q14050 COL9A3 5.9884
13342 Vinblastine Q14050 COL9A3 5.9115
5978 Vincristine Q14050 COL9A3 5.7568
5743 Dexamethasone Q14050 COL9A3 5.8115
5453 Thiotepa Q14050 COL9A3 5.6851
40839 Vindesine P01730 CD4 6.1276
13342 Vinblastine P01730 CD4 6.0338
5978 Vincristine P01730 CD4 5.8116
5743 Dexamethasone P01730 CD4 5.9288
40839 Vindesine P32248 CCR7 5.9338
13342 Vinblastine P32248 CCR7 5.8254
5743 Dexamethasone P32248 CCR7 5.7351